Sexual Side Effects: What Medications Cause Them and How to Manage Them

When a medicine helps your body in one way but hurts your sex life in another, it’s not just frustrating—it’s isolating. Sexual side effects, changes in desire, arousal, or performance caused by medications. Also known as drug-induced sexual dysfunction, these issues are far more common than most people admit. You might be taking something for depression, high blood pressure, or even acne, and not realize it’s quietly lowering your libido or making it harder to get or keep an erection. This isn’t weakness. It’s chemistry.

Many antidepressants, especially SSRIs like sertraline and fluoxetine are known to dampen sexual response. Studies show up to 70% of people on these drugs report some form of sexual side effect—lower desire, delayed orgasm, or even complete loss of arousal. Erectile dysfunction, the inability to achieve or maintain an erection isn’t just about aging or stress. It’s also linked to common meds like beta-blockers, diuretics, and even some cholesterol drugs. And if you’re taking something for prostate issues or hair loss, like finasteride, a drug that blocks hormones tied to both hair loss and sexual function, you’re in a group where this side effect is well-documented and often overlooked.

Here’s the thing: you don’t have to just live with it. Doctors don’t always bring this up first, but you can. There are alternatives—switching meds, adjusting doses, adding treatments like phosphodiesterase inhibitors, or even trying non-drug approaches like therapy or lifestyle changes. The posts below cover real comparisons: how certain pain meds, antidepressants, and ED treatments affect your sex life, what alternatives exist, and how to talk to your provider without shame. You’ll find honest breakdowns of what’s happening in your body, why it’s happening, and what steps actually work. This isn’t about avoiding meds—it’s about using them smarter, so your health doesn’t come at the cost of your intimacy.

Sexual Side Effects from Common Medications: What You Need to Know

Many common medications-from antidepressants to blood pressure pills-can cause sexual side effects like low desire, erectile dysfunction, or trouble reaching orgasm. Learn which drugs are most likely to cause problems and what you can do about them.

Written by

Edward Jepson-Randall, Oct, 31 2025