Addison's Disease in Dogs: Symptoms, Causes, and Treatment Options

When a dog has Addison's disease in dogs, a condition where the adrenal glands don’t produce enough cortisol and aldosterone. Also known as canine adrenal insufficiency, it’s not common—but when it happens, it can be life-threatening if missed. Unlike humans, dogs don’t usually show stress-related fatigue first. Instead, they might suddenly lose interest in food, vomit, shake, or collapse after exercise. These aren’t just "off days." They’re red flags for a failing hormone system.

This condition is often called the "great imitator" because its symptoms look like so many other problems—gastrointestinal upset, kidney issues, even poisoning. But here’s what sets it apart: the symptoms come and go, then suddenly get worse. Many vets miss it because the blood tests look normal until the dog crashes. That’s why knowing the subtle signs matters. A dog with Addison’s might seem fine one day and barely able to stand the next. The root cause? The adrenal glands stop making enough cortisol, the body’s main stress hormone and aldosterone, the hormone that controls salt and water balance. Without them, the body can’t handle physical stress, whether it’s a long walk, a visit to the vet, or even hot weather.

Most cases happen in young to middle-aged female dogs, especially breeds like Standard Poodles, Portuguese Water Dogs, and Bearded Collies. But any dog can get it. The good news? Once diagnosed, it’s manageable. Treatment usually means daily pills to replace the missing hormones, or monthly injections. Many dogs go on to live normal, happy lives—no different from their healthy peers—once they’re on the right dose. What you need to watch for is the balance: too little hormone and the dog crashes; too much and they become overly thirsty, urinate constantly, or develop muscle weakness. Regular blood tests are non-negotiable.

What you’ll find in the posts below aren’t just general overviews. These are real, practical insights from vets and dog owners who’ve been through this. You’ll see how symptoms show up differently in each dog, what bloodwork actually reveals, how to spot an Addisonian crisis before it’s too late, and which treatments work best without breaking the bank. Some posts even cover what to do if your dog’s meds run out on a weekend. This isn’t theory. It’s what works when your dog’s life depends on it.