When you reach for NSAIDs, nonsteroidal anti-inflammatory drugs used to reduce pain, fever, and inflammation. Also known as non-narcotic pain relievers, they’re one of the most common types of medication people take daily—for headaches, back pain, arthritis, or even a bad menstrual cramp. But taking them without knowing the risks is like driving without checking your brakes. Ibuprofen, a widely used NSAID found in brands like Advil and Motrin, can cause stomach bleeding after just a few days of regular use. Naproxen, another common NSAID sold as Aleve, lasts longer but carries similar risks. And celecoxib, a COX-2 inhibitor marketed as Celebrex, was designed to be gentler on the stomach, but it’s not risk-free—especially for people with heart problems.
NSAID safety isn’t one-size-fits-all. Someone with high blood pressure might need to avoid them entirely. Older adults, people on blood thinners, or those with a history of ulcers are at higher risk. Even healthy people can get hurt if they take too much or mix them with alcohol. Studies show that over-the-counter NSAIDs cause more hospital visits than many prescription drugs combined. The problem isn’t the medicine itself—it’s how we use it. We treat them like candy, popping them for minor aches without thinking about long-term damage. But your stomach lining, kidneys, and heart don’t work the same way they did when you were 20. What felt fine last year might cause serious trouble this year.
That’s why the articles below matter. You’ll find real comparisons between NSAIDs and alternatives, clear breakdowns of who should avoid them, and practical tips to reduce harm without giving up pain relief. We cover how Celebrex stacks up against ibuprofen and naproxen, why some people should never take certain NSAIDs, and how to spot early signs of internal damage before it’s too late. No fluff. No marketing. Just what you need to know to use these drugs safely—and when to walk away.
Topical meds deliver pain relief with far less risk than oral pills. Learn how systemic absorption affects safety, effectiveness, and which option is right for your pain.